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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '394458340355629636424a992efd0266b11463937f6dd067e745f755f2da1c87' 
  AND token = '32znD5eeY5xAsNLbftR4bG2g1e0hAYx2XK3OGx7MfcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}