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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b72b0e98af764e23f681eb8e764932706ab20dbfd6488c66205a5b9ec54383' 
  AND token = 'o45dRSMmRZ1vq89PXi+hV7+K626yVh6UhvY3pYUwaKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}