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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3378254384280d570180a3b2a5a83463114c49ace55b24e242f7a27cd53a10e' 
  AND token = 's1ejm0//QQbd4ILg8Nzp7S94QDeMm7aPEnne2tMdp9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}