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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4a283932d911bf51dc22494c76e6148582b1eee8044356d21118b3dea972e2' 
  AND token = 'FSEWJS9V2mw9/YD9By7E/rg95F8t2hQAtMnUZb2yTSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}