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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5454bf25beb08d325bae006ef92a238598f08effc1a8229dd5448c89471b8352' 
  AND token = '3It9qgENyZ/oGHUpwVXgRI1eFg2AcTu23POlEf8aZgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}