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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba66c681b3e85ff572384885bda9a5aa4a86c78146155f8ff2da4784edb1af54' 
  AND token = 'YfL+cZ2rdWm2aKDjuEOjm/K7D5WNphuGpVDqNP7Isro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}