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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed93219a011603aa0485d2239ff213891e7f9d5c2fa7fb4a0b7f83c66143b599' 
  AND token = 'FPOeTqWehlvOx3fB10FsgtP76VJY316x3RUjpIgaOwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}