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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82521b6f68d872279a95bfb34d1355060f675e6183b47bbe2e51b472a7ef3f77' 
  AND token = 'GJSDkaUV2Y1Txjy3EdVf582IZrPKtjv7womxjgeMjt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}