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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa94e9cd3914e7aa084a08c01847b85a0fc89205b894b8ce8c7e2235ab0f90a' 
  AND token = 'XntHK5WugV1/gfJIK/pZtQfGzH3VaiCnYPI9B0b9aGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}