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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5500fc68ca899498635d8287f60f87eef2bf61b536b0ae6be1e0b7f9332a0d0' 
  AND token = 'LHhrEzf7rrgp4WAFmrq5+oq+/CdLXJnknL6CQ/C70p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}