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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38e2c0c3e1059a9d7014f52c175211aedc4e4d3168ce64c642364f3d3efb8ee2' 
  AND token = '9dlY1D0gOR3MGsNqSqGPKpVGB9gicCLVgdA7jWn1c2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}