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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9c11649a47c7aee2979cb2a036bb7a0816961a981010c6865ab735060583f81' 
  AND token = 'vyG5OmHRzDwsn/2G33LsuVhnyx/0aookgwgPIo35m/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}