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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4de80c683b7a4379ade79f4744206a9b851c1d59a8dffb70e38ca7e5fac85c' 
  AND token = 'D5xNFQtRJQBrlIBOpJJuChxTomAWFdt+riKZ1zTLi+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}