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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678bd17302576d523fb7a0671d9405d7042eda814330fd41cedb036f537a06ee' 
  AND token = 'We3UQD0pOpA3owtjgzWVNc5pRwZClOVEgnmK44LfhdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}