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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fd4c3625a01bee93c8c54b3101f6c7c75904d217abbf9f0e207c7672a496ec5' 
  AND token = 'UZZTUqfSo/sOyxWb4Kdz4AxYr30CMPVwjeMT6mMSVTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}