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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede0c47e6976dd9e19674085b037263b40727e62c000bfb1cde55defba47c0f1' 
  AND token = '1hS4iYqUae/o26pZFbF/Y+a848Nl+f19sq9dgTtWHAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}