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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729024e4192c8b53908e6fd07839adeb97decd54d59213eabd212c8d0910c95a' 
  AND token = '3cZlU5f1SLBUsJV9c4+jEyfoXURsZjemOedJt0PJDiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}