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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef60fdc72e818fbd9120f810597b929973b10338410d960d63ae5710c3c87c07' 
  AND token = '6oqy4sR6AgUkJ9If5QkTtW37TWhnh6AixjPS9hRiM1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}