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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '394bb008d0d055a7efefb0eb84596b4e4d50f7ac890eac7a58ca1f3c3ccbabb6' 
  AND token = 'U9A1QEkVEHRAf7mguQiDBYvuRZy6IZ1CoQACwCTWlhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}