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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68365add8e0c24b91e6ff94a4b88df97fdf9ada7fb786bdbee17ba470b298264' 
  AND token = '+bG13t9+MoQCrZYW/eM2mxLsVtIpv/4gL35YWsSgUlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}