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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef843c591f78fb0956df9e8e9a72b60c002ebe536b3b7560642bacd42acee30' 
  AND token = '21bvOEX8o2/mRVcR1SxKa//lC5CJWXFx9A0lxioHTr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}