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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a448d2d3886865655a0710565519509117da6c9b74df1ea6dbd1dd086fd227d4' 
  AND token = 'cW0nBDOjeGgffagMPZ1L6j/AH5JeHD2Q3kd8r5LDfYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}