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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2a8c97d14ff241c4e312e9fa73a261971b8143d51c0eede6e0a58421c7fe6ff' 
  AND token = 'R+jc+7e/7rS5wXhtC/mystWi9ZJyJdSgIYmHxtCqz4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}