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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65d220627aa67dd8df5d982805c433decdc5b389b65dc9b8dee5e034af32ab8' 
  AND token = 'yUGXv9xzpRHvIUOUaM56pG3E6zZItfJisb3OCrA1z6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}