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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d67b0933e5e37dee766c034aa093eeb36f573d0a22005203d13335c8ef2de20' 
  AND token = 'DjR5IM/Ub4gszhT+sPQVJjkjeoa/Xci4BxEDM6rzHhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}