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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22a1371c559c5ee6245d0e1aa88de7ef7a364c25f67d2b177402e5df12e1f9e' 
  AND token = 'zyQaAevLwscp1/HFnO31u5HW8JIAt7w9pKHzYJiG9ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}