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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7be6c040fbd75cf8eb778ceadc8c532e873f2aab9d72ff0e25c5e2ee43e3792' 
  AND token = 'C7RX2KTJ9D8/xge3cg0/ozAjvRRUeB4JNqaVbTWp6Vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}