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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7863cc23ebe78ffd78a2e077e3debd0a1981d0eeed62d7cd468e98335abba84' 
  AND token = 'Te6iONGnGRJhHDg4lRpX0otePGdUMeZI6dPRNDnm/vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}