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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2569b50343f7550693f0093c1ea8500f336a0fa7b621944d49b9d20a59a17014' 
  AND token = 'Gvwc1h6MffpZURWadHrdZQFEATpJEPjuSUzmYe27eTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}