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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a9815a13a2cfcc4485c5f2875f3ba43b3f8494e5dbef85e6c9b7c5f046ea53' 
  AND token = 'wpgoEW+I6k1ouV+w3/7ub+Uu0msXp5iISDg7AmarOwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}