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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf4e2e46c759a4d7c34737415e9481e4d7e3baa83e248759902e2cd3b69b88a' 
  AND token = 'TUjQdxXt9YvqLYokcb1yHW0PSG+jFtt1vrsvZfRyQ6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}