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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180c38164638f63d181610993797b626f825ef8dfc48c691fbeda60bf3d0dceb' 
  AND token = 'j4ej0me5BTuQbtFb73DkukT5GtfZV5xU/ao7j/z8ogc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}