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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c10a7a9ea964c7fa8781b473ac8f3069f07f9f346acf909f7be9146acff9c24' 
  AND token = 'FqkAzII+uavY+P+DRBs3Uob7oBWB9rZBo/I0n0A5nYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}