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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8819f291fe0694fbfb630d4750ef81d80576dcee63f32fd7c8a17e1668a892cb' 
  AND token = 'TiBmRmC0lF388MbyL1I6jmg/ysoSSMLX5KgzamyEYio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}