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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7a413c949dd8d5e01fe94e1a309d316ed13d87883117e57588a0c5080339c9' 
  AND token = 'tC8OIGwxuglm4wiaxcdQvmq/v3yJC+lOTK0NJfRLUJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}