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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afff6991a829483c372875bef27ca72762d2aad232b6995079d808fde3c0fb95' 
  AND token = 'Zns4bH3uA3jotywOD+TAYshAuzZwz249ei4ahxla1CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}