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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26181410fe2ff47b936b3e790c1545acdebcd88d16f3dee42e668e6e2a72a73d' 
  AND token = 'of8Pye7Je9GYTPOOqIa7AO6VckEMt9CgWmGFbjFfWkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}