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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b4577c2f88308a34fead70549f0233bbc9e1cf7786288352c1f6544593e2af7' 
  AND token = 'ih7l4Uxf5wBdycBVl2cDU0MfuYLXkAGzzcFJnmKxNeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}