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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '562053cac1f280b27b78421039f5c49e671d69fd0c9b31aa209cded341b6191a' 
  AND token = 'VTeR9a3UK0s6Sjo2KvkdH1fdZFVYmIn2oDmegIrDOLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}