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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8389614bcd93af17a93d0feb6db66c3be992a19308ce0453cc74b1945e3970e1' 
  AND token = 'OLhmKD1OqNFPyjklJYEkzXPv9xofPtfYJ78e0tdBlJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}