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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48eb66c31080e729d9f95dfd39c5856d5e8a7b9f318da64d4473b09763328ab5' 
  AND token = 'V++GpoIs8F8xWqwxqndtqn9TgCxC6S1DA1NKKG+ER6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}