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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5993fdb31f6699e4c5373850db31c95975ecea3d974eeaa8879f57efc76326' 
  AND token = 'TPBrEGMQg+9Tfp+ZuDgk0e+W7CBV+95jRmAkoe5Ules=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}