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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3fc6e134abb756da5d1c9ad5c5489c5547868321666ca9850aa33f443ee165' 
  AND token = 'bfNLVe+xxlfhU/58d8z9RnTZG2C8JsCmHIr0gbOHBB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}