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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa110006f22f6f2137f10cbcbb3c416b8299858951c408fb47b099cc10144e66' 
  AND token = 'yZ1iJKERhkz2WAPR5v1+kHPPdzoMS5JfAkx9z8STlRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}