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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c66e21d871af28f037c513b35db68a496804a23065980edfdc258d5deb921d' 
  AND token = '3AGOmiYJ12faMR3JS9ipPDpvYANNZc72eeJ29rjFyGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}