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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9f5f162a1ba50502061707b96696ebd8edd024ae450aed2c8b8c86f93d1515' 
  AND token = 'FVGutH3Y/saWmdyAukjF0x6gxDjy2f2c+L+VfYkuoZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}