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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9445037d940e8b2db807fa48c3c7f72088e398ab2955095b52963c7a9d0cef87' 
  AND token = 'vxcXuktVXvETTrW8Q19JP54Y6YHj5Hifs3Ae5QTTNEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}