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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e63d469ab5531c52a675d9fae179836370a2c723c76d894a74309e0f68b1066' 
  AND token = 'MNljs9dfwCULtvx+qtdLNTJvsoIcVygmYkRXvpeLk4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}