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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '117e838421dd337a3feae017f6cab1899ca805108a9d0ee16bcb5fe8d686c6c1' 
  AND token = 'Fu7CE2EZIYGERbuNtIXQCRh7JJZQjm4mLogkHRBqyMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}