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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66aec99c7b4bfede2790b5369a551c7af72d80796bb9ae0872c7c06e924d0263' 
  AND token = 'k9/7poJ2v8JcTspAW2c2eVFrnUvF6Hedb8su02bXSRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}